calthaus / ncov-cfr

R code and documentation to estimate case fatality ratio of COVID-19 from cases outside China
GNU General Public License v3.0
90 stars 17 forks source link

Inclusion/exclusion of countries with new epidemics #5

Closed salervm1 closed 4 years ago

salervm1 commented 4 years ago

With many new local outbreaks (and more to come), how are you going to proceed with updating the analysis? Specifically, are countries going to be included/excluded from the analysis in order to retain the ability to catch the whole spectrum of disease, or will all data be included? I presume that expanding epidemics in countries with poor surveillance could result in data that is biased towards severe cases, as in the case of Hubei province.

Bonus question: is there a book on epidemiology you would recommend for someone with a math/comp sci background?

calthaus commented 4 years ago

You're exactly right. Including the cases in Iran or Italy, for example, would introduce an undesired bias in our analysis. We will probably stop updating the real-time estimation or limit the analysis to countries where we hope to have (almost) complete surveillance.

There are a number of books that could be of interest for you:

salervm1 commented 4 years ago

Thanks for your reply and recommendations!

umran commented 4 years ago

Would the Diamond Princess be a good sample to estimate CFR from? I ask because probably all cases were detected by testing the whole population onboard. If the population onboard is not too biased and people were infected randomly, perhaps it could tell us a thing or two about the clinical spectrum of COVID-19 we might expect to see in a larger population?