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cancerit / BRASS

Breakpoints via assembly - Identifies breaks and attempts to assemble rearrangements in whole genome sequencing data.
GNU Affero General Public License v3.0
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Unstable results - multiple possible normal panel intersections #60

Closed keiranmraine closed 7 years ago

keiranmraine commented 7 years ago

It is possible for the normal panel to include multiple possible hits which overlap with an event.

It is also possible for both events to have the same number of contributing samples and within those the same number of total contributing reads.

The only way to cope with this is to order the data and select the first entry after binning by:

  1. Total samples contributing
  2. Total reads from contributing samples
keiranmraine commented 7 years ago

Also discovered an error relating to the first entry of each of the raw groups being lost in all cases.