Can it work without matched control?

cancerit / ascatNgs

Somatic copy number analysis using WGS paired end wholegenome sequencing

http://cancerit.github.io/ascatNgs/

GNU Affero General Public License v3.0

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Can it work without matched control? #28

Closed alkodsi closed 8 years ago

alkodsi commented 9 years ago

Hi, ascat can work without a matched control when analysing array data. Is it possible to do the same with ascatNGS? I tried with unmatched control and the BAF was a mess and affected the absolute copy number inference.

keiranmraine commented 8 years ago

Hi, unfortunately the current ascatNgs implementation is not intended for unmatched analysis.