search

cancervariants / fusions

A repository for tracking documents, issues, and tools for the VICC / ClinGen gene fusion curation SOP
0 stars 0 forks source link

FGFR2 Fusions #7

Closed ahwagner closed 3 months ago

ahwagner commented 3 years ago

From Albrecht Stenzinger:

A nice and clinically very relevant example (for a manuscript) might be FGFR2 fusions (in cholangiocarcinoma). They come in several different flavors including fusions leading to a loss of regulatory elements. Complementing promotor switches and chimeric proteins.

Here is a recent paper on this topic which might be of interest: https://cancerdiscovery.aacrjournals.org/content/11/2/326