Colab Notebook Showing Use of MTI with Arbitrary Text

[cannin]

Can you make an example showing how to use MTI with pyjinius for arbitrary text? Just get back the results, you don't have to "process" them

R-HSA-164843    2-LTR circle formation  The formation of 2-LTR circles requires the action of the cellular non-homologous DNA end-joining pathway. Specifically the cellular Ku, XRCC4 and ligase IV proteins are needed. Evidence for this is provided by the observation that cells mutant in these functions do not support detectable formation of 2-LTR circles, though integration and formation of 1-LTR circles are mostly normal. The reaction takes place in the nucleus, and formation of 2-LTR circles has been used as a surrogate assay for nuclear transport. It has also been suggested that the NHEJ system affects the toxicity of retroviral infection.

R-HSA-73843 5-Phosphoribose 1-diphosphate biosynthesis  5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) is a key intermediate in both the de novo and salvage pathways of purine and pyrimidine synthesis. PRPP and the enzymatic activity responsible for its synthesis were first described by Kornberg et al. (1955). The enzyme, phosphoribosyl pyrophosphate synthetase 1, has been purified from human erythrocytes and characterized biochemically. The purified enzyme readily forms multimers; its smallest active form appears to be a dimer and for simplicity it is annotated as a dimer here. It specifically catalyzes the transfer of pyrophosphate from ATP or dATP to D-ribose 5-phosphate, and has an absolute requirement for Mg++ and orthophosphate (Fox and Kelley 1971; Roth et al. 1974). The significance of the reaction with dATP in vivo is unclear, as the concentration of cytosolic dATP is normally much lower than that of ATP. The importance of this enzyme for purine synthesis in vivo has been established by demonstrating excess phosphoribosyl pyrophosphate synthetase activity, correlated with elevated enzyme levels or altered enzyme properties, in individuals whose rates of uric acid production are constitutively abnormally high (Becker and Kim 1987; Roessler et al. 1993).<P>Molecular cloning studies have revealed the existence of two additional genes that encode phosphoribosyl pyrophosphate synthetase-like proteins, one widely expressed (phosphoribosyl pyrophosphate synthetase 2) and one whose expression appears to be confined to the testis (phosphoribosyl pyrophosphate synthetase 1-like 1) (Taira et al. 1989; 1991). Neither of these proteins has been purified and characterized enzymatically, nor have variations in the abundance or sequence of either protein been associated with alterations in human nucleotide metabolism (Roessler et al. 1993; Becker et al. 1996), so their dimerization and ability to catalyze the synthesis of PRPP from D-ribose 5-phosphate are inferred here on the basis of their predicted amino acid sequence similarity to phosphoribosyl pyrophosphate synthetase 1.

[PritiShaw]

This can also be achieved using a CURL request

curl -X POST https://ii.nlm.nih.gov/cgi-bin/II/Interactive/interactiveMTI.pl \
-H 'content-type: multipart/form-data;' \
-F 'InputText= {Text to process}' \
-F Filtering=default_MTI \
-F Output=justFacts

[PritiShaw]

Hi Mentor I have made the Colab Notebook, here
I have used User Input for credentials and text and used them for extracting MeSH terms.
Is this the way you want to take the input? Thanks

[cannin]

This is good. One change, can you provide the "real" link to the JAR? In a "text" block can you put instructions on where it came from?

[PritiShaw]

This is good. One change, can you provide the "real" link to the JAR? In a "text" block can you put instructions on where it came from?

I have made the changes Link to Notebook

Thanks