search

cbg-ethz / pareg

Pathway enrichment computations using a regularized regression approach to incorporate inter-pathway relations in the statistical model.
https://cbg-ethz.github.io/pareg/
7 stars 3 forks source link

Properly specify response distribution #1

Closed kpj closed 2 years ago

kpj commented 5 years ago

For microarray data, p-values follow a beta-uniform mixture (see paper).

The following questions need to be addressed: