ccagc / QDNAseq

QDNAseq package for Bioconductor
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Directly loading counts matrix #110

Open shashwatsahay opened 2 years ago

shashwatsahay commented 2 years ago

Hi,

Is there a constructor which directly converts a bed file into a QDNAseq counts object.

I have a manually normalised count dataframe that I would like to convert into QDNAseq counts object.

chr bin_start   bin_end bin_len bin_ind normalised_counts   counts
1   1   1000000 999999  1   -1.0    -1.0
1   1000000 2000000 1000000 2   1.9563313228679595  6471.0
1   2000000 3000000 1000000 3   1.7959808612440193  5831.0
1   3000000 4000000 1000000 4   2.1815908104054 5006.0
1   4000000 5000000 1000000 5   1.8522823862440945  4386.0
1   5000000 6000000 1000000 6   1.7374568288854002  4411.0
1   6000000 7000000 1000000 7   2.0295699960076092  5871.0
1   7000000 8000000 1000000 8   1.7201969234365184  5333.0
1   8000000 9000000 1000000 9   2.1330930294195602  5832.0
1   9000000 10000000    1000000 10  1.7651345542717536  6528.0
1   10000000    11000000    1000000 11  1.8698060381177264  5774.0
1   11000000    12000000    1000000 12  1.9361234254467337  5388.0
1   12000000    13000000    1000000 13  1.8358008110726192  5064.0
1   13000000    14000000    1000000 14  -1.0    -1.0
1   14000000    15000000    1000000 15  1.7447801574292559  4387.0
1   15000000    16000000    1000000 16  1.7856350898568385  5841.0
1   16000000    17000000    1000000 17  1.8243780648454042  5990.0
1   17000000    18000000    1000000 18  1.8388992465260687  5499.0
1   18000000    19000000    1000000 19  1.7154621040335325  5088.0
1   19000000    20000000    1000000 20  1.7935685094126652  6261.0
1   20000000    21000000    1000000 21  2.2186218332868144  6120.0
1   21000000    22000000    1000000 22  1.716944375105414   5763.0
1   22000000    23000000    1000000 23  1.811195901200985   6212.0
1   23000000    24000000    1000000 24  1.9318113465481888  6720.0
1   24000000    25000000    1000000 25  2.018586800954148   5174.0
1   25000000    26000000    1000000 26  1.900484277627135   5428.0
1   26000000    27000000    1000000 27  1.933725976174956   6113.0
1   27000000    28000000    1000000 28  1.957852620181039   6715.0
1   28000000    29000000    1000000 29  1.7993508052571678  5227.0
1   29000000    30000000    1000000 30  1.827352659926606   5063.0
1   30000000    31000000    1000000 31  1.8821740975232326  5123.0