[ ] In fetchCaddAnnotations.ts, if a gene is larger than 600,000 base pairs, CADD annotation is not performed. In this case, the frontend should display a message indicating that CADD annotation has not been performed. For example, "Gene of size 700,000 bp is too large to annotate with VEP. Annotating with gnomAD only!"
This is the desired behavior because the server does not have enough RAM to handle the subsequent matching between variant data and CADD variant annotation. Eventually, when the HPF Slurm automation is ready, CADD annotation will be performed for all genes even if they are larger than 600,000 base pairs.
[ ] In
fetchCaddAnnotations.ts, if a gene is larger than 600,000 base pairs, CADD annotation is not performed. In this case, the frontend should display a message indicating that CADD annotation has not been performed. For example, "Gene of size 700,000 bp is too large to annotate with VEP. Annotating with gnomAD only!"This is the desired behavior because the server does not have enough RAM to handle the subsequent matching between variant data and CADD variant annotation. Eventually, when the HPF Slurm automation is ready, CADD annotation will be performed for all genes even if they are larger than 600,000 base pairs.