I am using Carveme to construct an Eukaryotic model and trying to use one SBML model as universe model from attached zip folder...but getting following error..can you please guide me through this...
Reported 0 pairwise alignments, 0 HSPs.
0 queries aligned.
Traceback (most recent call last):
File "carve", line 364, in
ref_score=args.reference_score
File "carve", line 125, in main
universe_model = load_cbmodel(universe_file, flavor=config.get('sbml', 'default_flavor'))
File "C:\Users#####\AppData\Local\Continuum\anaconda3\envs\py36\lib\site-packages\framed\io\sbml.py", line 148, in load_cbmodel
fix_cb_model(model, flavor=flavor)
File "C:\Users#####\AppData\Local\Continuum\anaconda3\envs\py36\lib\site-packages\framed\model\fixes.py", line 22, in fix_cb_model
fix_cobra_model(model)
File "C:\Users#####\AppData\Local\Continuum\anaconda3\envs\py36\lib\site-packages\framed\model\fixes.py", line 47, in fix_cobra_model
clean_bounds(model)
File "C:\Users#####\AppData\Local\Continuum\anaconda3\envs\py36\lib\site-packages\framed\model\fixes.py", line 104, in clean_bounds
if reaction.lb <= -threshold:
TypeError: '<=' not supported between instances of 'NoneType' and 'int'
Dear Daniel,
I am using Carveme to construct an Eukaryotic model and trying to use one SBML model as universe model from attached zip folder...but getting following error..can you please guide me through this...
Reported 0 pairwise alignments, 0 HSPs. 0 queries aligned. Traceback (most recent call last): File "carve", line 364, in
ref_score=args.reference_score
File "carve", line 125, in main
universe_model = load_cbmodel(universe_file, flavor=config.get('sbml', 'default_flavor'))
File "C:\Users#####\AppData\Local\Continuum\anaconda3\envs\py36\lib\site-packages\framed\io\sbml.py", line 148, in load_cbmodel
fix_cb_model(model, flavor=flavor)
File "C:\Users#####\AppData\Local\Continuum\anaconda3\envs\py36\lib\site-packages\framed\model\fixes.py", line 22, in fix_cb_model
fix_cobra_model(model)
File "C:\Users#####\AppData\Local\Continuum\anaconda3\envs\py36\lib\site-packages\framed\model\fixes.py", line 47, in fix_cobra_model
clean_bounds(model)
File "C:\Users#####\AppData\Local\Continuum\anaconda3\envs\py36\lib\site-packages\framed\model\fixes.py", line 104, in clean_bounds
if reaction.lb <= -threshold:
TypeError: '<=' not supported between instances of 'NoneType' and 'int'
Data_Sheet_2_Multi-Omics and Genome-Scale Modeling Reveal a Metabolic Shift During C. elegans Aging.ZIP
PS: I also imported libsbml using 'conda install -c sbmlteam python-libsbml'
Thanks, Sonal