cerebis / qc3C

Reference-free quality assessment for Hi-C sequencing data
GNU Affero General Public License v3.0
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Improve comment about fraction of reads starting with site #15

Closed cerebis closed 5 years ago

cerebis commented 5 years ago

The 50% GC prediction is informative but not used to its best.

When a user supplies the wrong enzyme, the number of observed reads starting with cut-site is likely to be close to this value (assuming true mean GC is not far off 50%). We should flag to users when these values are close.