cerebis / sim3C

Read-pair simulation of 3C-based sequencing methodologies (HiC, Meta3C, DNase-HiC)
GNU General Public License v3.0
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How to use sim3C to generate hic simulation data of different lengths according to the restriction site? #41

Open xujialupaoli opened 1 week ago

xujialupaoli commented 1 week ago

Hello, thank you for providing such a useful software. Can I use sim3C to generate hic data that is disconnected according to the restriction site? Instead of 150bp data with regular R1 and R2? I can generate 150bp hic simulation data using the following code . Do you know how to adjust it?

sim3C --profile mycom.txt -n 5000000 -l 150 -e DpnII -m hic /home/work/jialu/tetraploid_assembly/simulate_data/strain_fq/ref_genome/hap1.fa hap1_R1.fq hap1_R2.fq

Looking forward to your reply!