search

cerebis / sim3C

Read-pair simulation of 3C-based sequencing methodologies (HiC, Meta3C, DNase-HiC)
GNU General Public License v3.0
19 stars 5 forks source link

Basic support for IUPAC symbols #8

Closed cerebis closed 5 years ago

cerebis commented 5 years ago

When fully simlulating machine errors, Sim3C will raise an exception when reference sequences contain IUPAC ambiguity symbols. This is due to a lack of support for IUPAC symbols in the Art package.

Since this is annoying, at the very least we should have the choice to handle any encountered IUPAC as an N.

A more complete fix is not planned as this would require IUPAC symbols to be modelled within Art.

cerebis commented 5 years ago

Whelp, I actually fixed this already in #5