Open Donaim opened 1 year ago
In our HXB2 reference, vpu region is the following sequence:
TQPIPIVAIV ALVVAIIIAI VVWSIVIIEY RKILRQRKID RLIDRLIERA EDSGNESEGE ISALVEMGVE MGHHAPWDVD DL*
It does not start with M, and thus is defective [1].
M
It probably does not matter much, since it's a 1 base SNP, at a region boundary. But it has some impact since most genomes do not have this mutation, and so they align worse.
In our HXB2 reference, vpu region is the following sequence:
It does not start with
M, and thus is defective [1].It probably does not matter much, since it's a 1 base SNP, at a region boundary. But it has some impact since most genomes do not have this mutation, and so they align worse.