Bugfix: --MD was not working properly due to the addition of --ds in the
last release (#1181 and #1182).
New feature: added an experimental preset lr:hqae for aligning accurate
long reads back to their assembly. It has been observed that map-hifi and
lr:hq may produce many wrong alignments around centromeres when accurate
long reads (PacBio HiFi or Nanopore duplex/Q20+) are mapped to a diploid
assembly constructed from them. This new preset produces much more accurate
alignment. It is still experimental and may be subjective to changes in
future.
Change: reduced the default --cap-kalloc to 500m to lower the peak
memory consumption (#855).
Notable changes to mappy:
Bugfix: mappy option struct was out of sync with minimap2 (#1177).
Minimap2 should output identical alignments to v2.27.
(2.28: 27 March 2024, r1209)
Minimap2-2.27 (r1193)
Notable changes to minimap2:
New feature: added the lr:hq preset for accurate long reads at ~1% error
rate. This was suggested by Oxford Nanopore developers (#1127). Whether
this preset works well for PacBio HiFi reads has not been tested.
New feature: added the map-iclr preset for Illumina Complete Long Reads
(#1069), provided by Illumina developers.
New feature: added option -b to specify mismatch penalty for base
transitions (i.e. A-to-G or C-to-T changes).
New feature: added option --ds to generate a new ds:Z tag that
indicates uncertainty in INDEL positions. It is an extension to cs. The
mgutils-es6.js script in minigraph parses ds.
Bugfix: avoided a NULL pointer dereference (#1154). This would not have an
effect on most systems but would still be good to fix.
Bugfix: reverted the value of ms:i to pre-2.22 versions (#1146). This was
an oversight. See fcd4df2 for details.
Bugfix: --MD was not working properly due to the addition of --ds in the
last release (#1181 and #1182).
New feature: added an experimental preset lq:hqae for aligning accurate
long reads back to their assembly. It has been observed that map-hifi and
lr:hq may produce many wrong alignments around centromeres when accurate
long reads (PacBio HiFi or Nanopore duplex/Q20+) are mapped to a diploid
assembly constructed from them. This new preset produces much more accurate
alignment. It is still experimental and may be subjective to changes in
future.
Change: reduced the default --cap-kalloc to 500m to lower the peak
memory consumption (#855).
Notable changes to mappy:
Bugfix: mappy option struct was out of sync with minimap2 (#1177).
Minimap2 should output identical alignments to v2.27.
(2.28: 27 March 2024, r1209)
Release 2.27-r1193 (12 March 2024)
Notable changes to minimap2:
New feature: added the lr:hq preset for accurate long reads at ~1% error
rate. This was suggested by Oxford Nanopore developers (#1127). It is not
clear if this preset also works well for PacBio HiFi reads.
New feature: added the map-iclr preset for Illumina Complete Long Reads
(#1069), provided by Illumina developers.
New feature: added option -b to specify mismatch penalty for base
transitions (i.e. A-to-G or C-to-T changes).
New feature: added option --ds to generate a new ds:Z tag that
indicates uncertainty in INDEL positions. It is an extension to cs. The
mgutils-es6.js script in minigraph parses ds.
Bugfix: avoided a NULL pointer dereference (#1154). This would not have an
effect on most systems but would still be good to fix.
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Automatic rebases have been disabled on this pull request as it has been open for over 30 days.
Bumps mappy from 2.17 to 2.28.
Release notes
Sourced from mappy's releases.
... (truncated)
Changelog
Sourced from mappy's changelog.
... (truncated)
Commits
8170693
Release minimap2-2.28 (r1209)e3d8c70
r1208: reverted RMQ gap coefficient119bdc6
r1207: reduced cap_kalloc from 1G to 500M89d4d21
r1206: enabled RMQ for lr:hqaef51ff1a
r1205: updated lr:hqae27b254e
backup; DON'T USE!!!c881b14
r1203: added preset lr:hqaef18dadb
r1202: halved RMQ gap costa83b8fe
r1201: renamed --dbg-seed-freq to --dbg-seed-occc22bfe7
r1200: added --rmq-inner and --dbg-seed-freqYou can trigger a rebase of this PR by commenting
@dependabot rebase
.Dependabot commands and options
You can trigger Dependabot actions by commenting on this PR: - `@dependabot rebase` will rebase this PR - `@dependabot recreate` will recreate this PR, overwriting any edits that have been made to it - `@dependabot merge` will merge this PR after your CI passes on it - `@dependabot squash and merge` will squash and merge this PR after your CI passes on it - `@dependabot cancel merge` will cancel a previously requested merge and block automerging - `@dependabot reopen` will reopen this PR if it is closed - `@dependabot close` will close this PR and stop Dependabot recreating it. You can achieve the same result by closing it manually - `@dependabot show