Census enables users to perform in silico experimentation to interrogate genes responsible for cell states recorded in the CELLxGENE metadata (e.g. cell type, disease, development stage, etc) using pre-trained models to enable biologists to quickly test hypotheses in an experiment-free fashion.
The work defined here is for the Discovery phase of this project. A product phase should be described elsewhere and once this discovery phase is finalized.
User stories
I am a computational biologist who wishes to understand what genes have the highest potential to:
Go from a cancer state to a healthy state.
Go from a differentiated state to pluripotent state.
Go from differentiate state to another differentiated state (e.g. B cell to to T cell)
Goals
To have a proposed testes method for in silico experimentation to be considered for production.
Discovery work
The deliverables are the following:
Landscape current methods.
Draft product requirements and validation strategies.
Assess feasibility or re-use of current models/embeddings.
pablo-gar
commented
6 months ago
Definition
Census enables users to perform in silico experimentation to interrogate genes responsible for cell states recorded in the CELLxGENE metadata (e.g. cell type, disease, development stage, etc) using pre-trained models to enable biologists to quickly test hypotheses in an experiment-free fashion.
The work defined here is for the Discovery phase of this project. A product phase should be described elsewhere and once this discovery phase is finalized.
User stories
Goals
To have a proposed testes method for in silico experimentation to be considered for production.
Discovery work
The deliverables are the following: