chembl / GLaDOS

Web Interface for ChEMBL @ EMBL-EBI
https://www.ebi.ac.uk/chembl/
Other
46 stars 6 forks source link

Mapping mutants for assay data #1216

Closed LivC193 closed 1 year ago

LivC193 commented 4 years ago

I am trying to generate compound-protein pairs that have an assay value associated. I see you map protein targets to Uniprot, but how do you deal in cases where the protein has been mutated ? Is there any way to get access to the mutated sequence ?

Emma-Manners commented 1 year ago

Yes, mutations are recorded in the variant_sequences table.

There is some additional information here - https://chembl.gitbook.io/chembl-interface-documentation/frequently-asked-questions/target-questions#how-does-chembl-treat-protein-variants

Thanks