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chembl / IDG

Issue tracker for the IDG interface
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Editing Molecular dictionary #98

Open Anneli15 opened 8 years ago

Anneli15 commented 8 years ago

Not sure why I can't edit, what else except a 3 should there be?

screen shot 2015-12-11 at 4 25 40 pm

Anneli15 commented 8 years ago

The compound AMG-706 (Motesanib) is now in the data base as Phase 0 as the system doesn't allow me to save anything else.

Anneli15 commented 8 years ago

Think I know why the system doesn't accept another phase number. It is probably because in Chembl all compounds that are not ph4 and approved are Phase 0. So using Chembl looup says that it has to be "0". I haven't noticed this problem before so something to do with the improved lookup?

revajk commented 8 years ago

Hi Anneli, This is to do with the cross validation of form data to the CHEMBL. The system now checks and validates all the information you have entered in the molecule dictionary and target dictionary form across CHEMBL before saving.

Anneli15 commented 8 years ago

I guessed as much but can it be changed so that it is possible to add another phase than 0?

revajk commented 8 years ago

I am not quite sure I understand, do you want the validation to be removed? Or should I not impose validation on few fields?

On 7 Jan 2016, at 09:54, Anneli15 notifications@github.com wrote:

I guessed as much but can it be changed so that it is possible to add another phase than 0?

— Reply to this email directly or view it on GitHub https://github.com/chembl/IDG/issues/98#issuecomment-169613690.

Anneli15 commented 8 years ago

Remove validation from the highest phase field if it doesn't allow me to change it from the 0 that is in Chembl to a 1, 2 or 3. If I can change it manually then it is fine. See above example i.e. cross validation is fine when it comes to name, structure relationships but it needs to be possible to change things like highest phase that will obviously be different depending on which phase in development the drug is.

revajk commented 8 years ago

Okie. Is there any other field in molecule dictionary that you might want to forgo validation? like Prodrug, blackbox warning etc?

On 7 Jan 2016, at 10:28, Anneli15 notifications@github.com wrote:

Remove validation from the highest phase field if it doesn't allow me to change it from the 0 that is in Chembl to a 1, 2 or 3. If I can change it manually then it is fine. See above example i.e. cross validation is fine when it comes to name, structure relationships but it needs to be possible to change things like highest phase that will obviously be different depending on which phase in development the drug is.

— Reply to this email directly or view it on GitHub https://github.com/chembl/IDG/issues/98#issuecomment-169623009.

Anneli15 commented 8 years ago

Maybe not prodrug but blackbox warning yes. Also fields like usan/inn name (or maybe these are different as the compound either has a name in chembl or not and I can add a name anyway)

revajk commented 8 years ago

Now you can change maxphase and blackbox warning even when you do shamble lookup.. I haven’t changed the validation for the rest of the fields. Changed the drug_type to be a dropbox.

Added ’Natural product’ to the list of choices in drug_type. Have increased the text size for target_type from 25 to 50.

On 7 Jan 2016, at 10:35, Anneli15 notifications@github.com wrote:

Maybe not prodrug but blackbox warning yes. Also fields like usan/inn name (or maybe these are different as the compound either has a name in chembl or not and I can add a name anyway)

— Reply to this email directly or view it on GitHub https://github.com/chembl/IDG/issues/98#issuecomment-169624600.