Reliability in the absence of biological replicates

chenlingantelope / MSscRNAseq2019

Analysis for 2019 submission "Integrated single cell analysis of blood and cerebrospinal fluid leukocytes in multiple sclerosis" Schafflick1, Xu, Hartlehnert1 et. al

MIT License

21 stars 8 forks source link

Reliability in the absence of biological replicates #1

Closed crushseven-7 closed 3 years ago

crushseven-7 commented 4 years ago

Hi there， I am working with a single cell project. I am tring to compare two groups' cluster abundance. There are biological replicates in each group in your paper, So is your algorithm reliable without biological duplication. Best

chenlingantelope commented 3 years ago

Hi,

I don't believe that the cluster abundance comparison test can be run without biological replicates.