HiFi reads: Is it better to perform assembly before taxonomic and functional identification?

[PeymanDerik]

Hello

I am a beginner and I have a question about metagenomic analysis using HiFi PacBio long reads. In short read metagenomics I have seen in some papers who suggest doing taxonomic and functional profiling after assembly, to increase the precision. I was wondering if with long reads we can directly use the raw reads for profiling or it is still better to perform assembly first.

Thank you

[chhylp123]

It would be better to open an issue here: https://github.com/xfengnefx/hifiasm-meta