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chhylp123 / hifiasm

Hifiasm: a haplotype-resolved assembler for accurate Hifi reads
MIT License
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problem of assembly #526

Open hchen815 opened 1 year ago

hchen815 commented 1 year ago

Hi, The previous reports on the plant we study on suggested it was diploid, but our own assembly results indicate that it may be a homologous tetraploid. The results are attached. Based on these findings, can we confirm that it is indeed a homologous tetraploid? If so, should we reassemble it using hifiasm? Do we need to adjust any parameters? if it is possible, could you please give us some suggestions on chromosome attachment?

assembly.pdf

chhylp123 commented 1 year ago

It looks like a tetraploid genome. It might be better to run purge_dups for the primary assembly of hifiasm.