Closed ghost closed 5 years ago
added, should appear shortly.
Hi Barry,
Can you please add Ines's name to Predicting Renal Failure project, maybe to the last sentence as:
"This work is in collaboration with Ines Sousa from University of Minho and John New from Salford Royal Hospital"
Best wishes
Ozgur
I was hoping she would give us her details so I can add her to the list of former group members. I'll ask again and that will mean she can appear as a name with a link to her page in the sidebar...
Hi Barry,
I was wondering could you please add the below two projects to the CHICAS webpage.
Thanks
Ozgur
1) Real-time monitoring of progression towards renal failure in primary care patients
Renal disease can be asymptomatic for many years, but early detection and treatment can slow the rate of progression towards renal failure. Analysis of routinely collected biomarkers of kidney function can assist early detection. Current UK guidelines use the estimated glomerular filtration rate (eGFR) as an overall measure of kidney function and recommend that a patient who is losing kidney function at a relative rate of at least 5% per year, as measured by their eGFR, should be referred to a specialist treatment centre. In this study, we consider use of dynamic linear modelling to obtain the predictive distribution of the underlying rate of change in kidney function. Our overall aim is to incorporate model-based predictions into a real-time surveillance system that can alert general practitioners to the possible need for the referral of their patient to a specialist treatment centre.
CHICAS people: Peter J Diggle, Ines Sousa, Ozgur Asar
External collaborators: John New from Salford Royal Hospital
Paper: Diggle PJ, Sousa I, Asar Ö (2014) Real time monitoring of progression towards renal failure in primary care patients. To appear in Biostatistics.
2) Investigating the influence of acute kidney injury on long-term kidney function
Acute kidney injury (AKI) corresponds to sudden falls of kidney’s excretion function in short term. It is common and catastrophic especially in hospitalised and critically-ill patients and has now been accepted as an important public health problem. However, the literature on the influence of AKI on proceeding kidney function is vague. In this study, we study the influence of AKI on long-term kidney function amongst patients who were identified as having chronic kidney disease.
CHICAS people: Ozgur Asar, Peter J Diggle
External collaborators: James Ritchie and Philip Kalra from Salford Royal Hospital