choderalab / openmmtools

A batteries-included toolkit for the GPU-accelerated OpenMM molecular simulation engine.
http://openmmtools.readthedocs.io
MIT License
253 stars 81 forks source link

Replica exchange method with AMOEBA force field and a customIntegrator #756

Open yongyouhe opened 1 month ago

yongyouhe commented 1 month ago

Hi, openmmtools devs!

I have been performing simulations with the all-atom AMOEBA force field using the MSTLangevinIntegrator. Recently, I wanted to use the replica exchange module of openmmtools to accelerate the simulations. However, I am unsure whether the module supports the AMOEBA force field (custom forces) and customIntegrators. If not, could you advise on which parts of the module should be modified to ensure compatibility?