number of chromosomes in the LDPred-2

choishingwan / PRS-Tutorial

A tutorial on how to run basic polygenic risk score analysis

MIT License

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number of chromosomes in the LDPred-2 #36

Closed fmadani closed 2 years ago

fmadani commented 2 years ago

Hi @privefl,

In the step titled "Calculate the LD matrix", in the chromosome based calculation, the number of chromosomes is considered 22 while there are 23 pairs in human cells. Is it a typo, or there is any other reason for considering 22? Please clarify.

Farshad

privefl commented 2 years ago

Sex chromosomes are often not used when making polygenic scores.