choishingwan / PRS-Tutorial

A tutorial on how to run basic polygenic risk score analysis
MIT License
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Question on PRS.summary file #41

Closed dzimmerman-amc closed 1 year ago

dzimmerman-amc commented 2 years ago

Hi there,

I just wanted to ask how PRSice chooses the best model fit in the .summary file. I am using a binary trait and it seems to choose the the threshold of 1 is best fit with all of my SNPs inlcuded. Additionally, is it possible to get the list of actual SNPs that are included under the Num_SNP column.

Thanks in advance!

Best wishes, Dominic

choishingwan commented 2 years ago

We just did a regression and find one resulting in highest R2.

use --print-snp to get the list

On Wed, Mar 9, 2022 at 10:53 AM dzimmerman-amc @.***> wrote:

Hi there,

I just wanted to ask how PRSice chooses the best model fit in the .summary file. I am using a binary trait and it seems to choose the the threshold of 1 is best fit with all of my SNPs inlcuded. Additionally, is it possible to get the list of actual SNPs that are included under the Num_SNP column.

Thanks in advance!

Best wishes, Dominic

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