PRSet: Question about Which Gene Set to Choose

[jueqiw]

Hi Dr Shing Wan Choi,

Thanks a lot for your interesting work! I am trying to run the PRSet on my target datasets about Alzheimer's disease and ASD. But I wonder, do you have any recommendations on which gene set I should choose from? Is it possible for you to share the MSigDB files and gene gtf files of the schizophrenia task with me?

Thanks in advance.

Jueqi

[choishingwan]

It’s an important research question and there really isn't a one size fit all solution

I’d recommend you to try and run MAGMA on the summary statistics on the msigdb sets

Sam

On Wed, Nov 13, 2024 at 7:36 PM Jueqi Wang @.***> wrote:

Hi Dr Shing Wan Choi,

Thanks a lot for your interesting work! I am trying to run the PRSet on my target datasets about Alzheimer's disease and ASD. But I wonder, do you have any recommendations on which gene set I should choose from? Is it possible for you to share the MSigDB files and gene gtf files of the schizophrenia task with me?

Thanks in advance.

Jueqi

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