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chrchang / plink-ng

A comprehensive update to the PLINK association analysis toolset. Beta testing of the first new version (1.90), focused on speed and memory efficiency improvements, is finishing up. Development is now focused on building out support for multiallelic, phased, and dosage data in PLINK 2.0.
https://www.cog-genomics.org/plink/2.0/
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Specifying pairs for IBD estimation #230

Closed idubinkin closed 1 year ago

idubinkin commented 1 year ago

Is there a way to calculate IBD only for specified pairs of individuals? For example, if I need to find relatives for only one individual in a set of a million, can I avoid computing 1’000’000x1’000’000 matrix and instead calculate just 1x1’000’000? Could it be achieved via retired --genome-lists option?

chrchang commented 1 year ago

See plink 2.0's --make-king-table command and --king-table-require flag.

idubinkin commented 1 year ago

Thank you, i'll look into that.