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chrchang / plink-ng

A comprehensive update to the PLINK association analysis toolset. Beta testing of the first new version (1.90), focused on speed and memory efficiency improvements, is finishing up. Development is now focused on building out support for multiallelic, phased, and dosage data in PLINK 2.0.
https://www.cog-genomics.org/plink/2.0/
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macOS: Impossible to open plink2 #279

Closed Will-Tyler closed 3 hours ago

Will-Tyler commented 3 hours ago

Description

I am trying to run plink2 on my MacBook Air. I downloaded plink2 from here by selecting the download link for Alpha 5.14 final for macOS M1.

When I try to run plink2 (./plink2), macOS displays a message saying that Apple cannot verify that plink2 does not contain malicious software and that the software needs to be updated.

Machine details

OS: macOS 14.6.1 23G93 arm64
Host: MacBookAir10,1
Kernel: 23.6.0
Uptime: 15 days, 1 hour, 37 mins
Shell: zsh 5.9
CPU: Apple M1
GPU: Apple M1
chrchang commented 3 hours ago

Compile from source if you are concerned about this.

Will-Tyler commented 3 hours ago

It is not just a concern. macOS will not let me run the downloaded plink2 because of this.

I was able to install a working plink2 through brewsci/bio, which I learned about through #253, not through any documentation.

In my opinion, this issue should remain open because the installation instructions do not work.

chrchang commented 1 hour ago

Apple has recently made this harder for users, but no, it's not impossible. If it ever becomes impossible, I may stop supporting macOS.