christophertbrown / iRep

scripts for estimating bacteria replication rates based on population genome copy number variation
MIT License
68 stars 9 forks source link

iRep for origin of replication #19

Open sarah872 opened 6 years ago

sarah872 commented 6 years ago

Can iRep be used for predicting the ori and ter of a draft genome sequence? Are there any temporary files that could be used for that information?

christophertbrown commented 6 years ago

iRep estimates the coverage values at the origin and terminus of replication, but does not identify where they are in the genome. Because genome coverage values can be somewhat noisy, there typically are multiple genomic regions with coverage values similar to those at the origin and terminus of replication, making it difficult to identify these regions.

On Feb 2, 2018, at 4:28 AM, sarah872 notifications@github.com wrote:

Can iRep be used for predicting the ori and ter of a draft genome sequence? Are there any temporary files that could be used for that information?

— You are receiving this because you are subscribed to this thread. Reply to this email directly, view it on GitHub, or mute the thread.