Dear all,
I have a multisample exome vcf file. Exome sequences were obtained with SureSelect Exome V6.
I would like to infer the ethnicity with EthSeq. However I am not sure which reference vcf (or gds file) should I use. I have used those implemented in the R package. However obtained results where far from perfect given the fact that a bunch of samples belong to gnomAD_AMR population. I have read the fact that some sequences could be formatted as a reference model with ethseq.RM. However I don't know which ones should I use as a reference.
Any advice will be really appreciated.
Regards,
Dear all, I have a multisample exome vcf file. Exome sequences were obtained with SureSelect Exome V6. I would like to infer the ethnicity with EthSeq. However I am not sure which reference vcf (or gds file) should I use. I have used those implemented in the R package. However obtained results where far from perfect given the fact that a bunch of samples belong to gnomAD_AMR population. I have read the fact that some sequences could be formatted as a reference model with ethseq.RM. However I don't know which ones should I use as a reference. Any advice will be really appreciated. Regards,