Most people interpreting variants rely on predefined filter, e.g. for population allele frequencies, Consequences, etc.
With these filters, a stepwise analysis of variants is possible and needed for bigger datasets, e.g. from WES and WGS.
The current implementation will allow interactive filtering within the HTML report. However, setting all filters every time the HTML report is opened is time-consuming, especially for complex filters.
Hence we should implement defining complex filters in the nextflow configuration which creates separate HTML and TSV tables that are accessible in the main HTML report. Hence, the user can easily switch between different filters through the dropdown menue.
This can be implemented by using the filter_vep or vembrane software and running it through the downstream TSV conversion and HTML report generation.
Description of feature
Most people interpreting variants rely on predefined filter, e.g. for population allele frequencies, Consequences, etc. With these filters, a stepwise analysis of variants is possible and needed for bigger datasets, e.g. from WES and WGS. The current implementation will allow interactive filtering within the HTML report. However, setting all filters every time the HTML report is opened is time-consuming, especially for complex filters. Hence we should implement defining complex filters in the nextflow configuration which creates separate HTML and TSV tables that are accessible in the main HTML report. Hence, the user can easily switch between different filters through the dropdown menue. This can be implemented by using the filter_vep or vembrane software and running it through the downstream TSV conversion and HTML report generation.