clemente-lab / mmeds-meta

A database for storing and analyzing omics data
https://mmeds.org
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expand options for rarefaction/depth values #438

Open adamcantor22 opened 1 year ago

adamcantor22 commented 1 year ago

Is your feature request related to a problem? Please describe. Currently, we have a standard filter and rarefaction for diversity of 1000. While this may be accurate for some studies, and we do have the ability to modify it prior to run, it is very often the case in which the amount of reads assigned will have a direct impact on what we want to rarefy at.

Describe the solution you'd like A dynamic evaluation of what rarefaction depth should be, perhaps at the lowest non-control read count above 1000.

Describe alternatives you've considered Could also be based on run/sample size.

Additional context Was going over this with Alba, needed to rerun some metrics at 10374 (lowest non-control) as opposed to 1000, as 1000 did not give enough detail.