cmungall / cell-ontology-DO-NOT-USE

Initial attempt to move repo from gcode. USE OBOPHENOTYPE
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Issue: macrophage EquivalentTo myeloid leukocyte #141

Open GoogleCodeExporter opened 9 years ago

GoogleCodeExporter commented 9 years ago
(Alex, this might be for you please?)

From email thread on GO Editors list: 

>> ADD GO:0014005 'microglia development' GO:0061515 'myeloid cell development'
>> DODGY
>>
>
> Thought so too, but microglia really are macrophages (see 
http://en.wikipedia.org/wiki/Microglia). Still, looking at the inference 
explanation in Protege, could there be a problem here?
> 'macrophage' SubClassOf 'myeloid leukocyte'
> should be develops_from? Something around the myeloid leukocyte/leukocyte 
link (which make 'microglia' a direct descendant of 'leukocyte') doesn't sound 
quite right to me, but I can't put my finger on it. Ideas?

See explanation (trivial - it's asserted in the genus of the definition)

You could put something on the CL tracker, I'm sure Alex (cc'd) can give a 
detailed answer (or fix if wrong)

For what it's worth, I think the textual definition is problematic:

"A mononuclear phagocyte present in variety of tissues, typically 
differentiated from monocytes, capable of phagocytosing a variety of 
extracellular particulate material, including immune complexes, microorganisms, 
and dead cells." 

Thanks,
Paola

Original issue reported on code.google.com by pa...@ebi.ac.uk on 9 Jul 2014 at 8:16

GoogleCodeExporter commented 9 years ago

Original comment by cmung...@gmail.com on 9 Jul 2014 at 3:55