betas and sds matrix preparation

cnfoley / hyprcoloc

R package for performing high dimensional multi-trait colocalization analyses using GWAS summary data

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betas and sds matrix preparation #8

Open Shicheng-Guo opened 2 years ago

Shicheng-Guo commented 2 years ago

Dear Chris,

Can you share some how to prepare beta and standard error matrix for genome-wide level summary statistics data from multiple traits? for example, MAF, MAC, P-value pre-filtering, how to select the genomic regions, etc?

Thanks.

Shicheng

Liuyh275 commented 5 months ago

hi，

I wonder if you have solved it? I am also confused about how to prepare beta and ses matrix for genome-wide summary statistics data from multiple traits. And it would be appreciated if you could share it with me.

Thanks, Yanhong Liu