search

cnio-bu / beyondcell

Beyondcell is a computational methodology for identifying tumour cell subpopulations with distinct drug responses in single-cell RNA-seq and Spatial Transcriptomics data.
Other
40 stars 4 forks source link

I have the same problem Imputing normalized BCS... #83

Closed Phoenix12580 closed 1 year ago

Phoenix12580 commented 1 year ago

Can I use other scRNA-seq imputation tools to the raw data and then input it into Beyondcell? Thank you very much.

SGMartin commented 1 year ago

Beyondcell requires a normalized single cell matrix. Whether the aforementioned matrix has been imputed or not should not matter. However, keep in mind that beyondcell's imputation happens over beyondcell scores and not over gene expression.

Phoenix12580 commented 1 year ago

Beyondcell requieres a normalized single cell matrix. Whether the aforementioned matrix has been imputed or not should not matter. However, keep in mind that beyondcell's imputation happens over beyondcell scores and not over gene expression.

Thank you very much