cole-trapnell-lab / garnett

Automated cell type classification
MIT License
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human developing brain #4

Closed Crockol closed 3 years ago

Crockol commented 5 years ago

Please provide the following info when submitting a new classifier:

Species: Tissue/sample: human fetal brain Author(s): Nicolò Caporale Data source (if you generated the data, indicate yourself): I used public available papers and datasets to generate a marker file with the gene signatures of the different cell types in the developing human brain Published? (if so provide DOI): https://cells.ucsc.edu/?ds=cortex-dev https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995803/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3668182/ https://www.ncbi.nlm.nih.gov/pubmed/27350034 https://www.ncbi.nlm.nih.gov/pubmed/29217575

Any notes, including whether/how you have validated This work was done in order to build a classifier for cortical brain organoids. I am currently working and training the marker file on a cortical brain organoid that we differentiated in the lab for 50 days. https://www.biorxiv.org/content/early/2018/12/02/484741 I still have to verify how good it is and how generalisable the classifier is for other organoid protocols or other stages of differentiation. Thus I thought that submitting it to the community could facilitate its spread, testing and optimization. If you have comments/critics/suggestions, contact me at nicolo.caporale@gmail.com

MarkerDevelopingBrainRefined.txt

hpliner commented 5 years ago

Thanks for this submission! Do you have the rdata file with the trained classifier to provide as well? You can save it using save(classifier, file="classifier")

hpliner commented 3 years ago

I'm going to close this, please reopen if you'd like to submit the classifier!