cole-trapnell-lab / monocle3

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principles behind label_leaves ordering #658

Open rasmirnov opened 1 year ago

rasmirnov commented 1 year ago

Hello developers,

Thanks for the creation of such a versatile tool.

Could you please clarify the idea behind the numeration of leaves in a graph. As far as I understood, the pseudotime is nothing but the reflection of distance from the root on the umap. But I was confused a bit with ordering leaves. How I can interpret it and which inferences I can made based on this? I just was surprised that the part of the cells with higher pseudotime was assigned to the 2nd leaves out of four on the figure below..

Will be grateful for any help!

micro_ptime_leaves