compbiomed / singleCellTK

Interactively analyze single cell genomic data
https://camplab.net/sctk/
Other
175 stars 77 forks source link

Incorporation of SCTransform and the ... argument into runDoubletFinder #762

Open professor-sagittarius opened 3 months ago

professor-sagittarius commented 3 months ago

Hi, thanks for creating such a useful and streamlined single cell analysis tool.

I was wondering if there were plans to incorporate SCTransform or create a ... argument for the runDoubletFinder function. The source code seems to suggest (e.g. with lines like if (sct == FALSE){ ) that the function was built to handle more flexibility within the Seurat workflow, but there is currently no option sct or ...

It would be nice to pass additional arguments (e.g. vars.to.regress in SCTransform) to the various steps of runDoubletFinder to more closely match the downstream workflow, such that observed clusters can be better approximated by runDoubletFinder.