cortes-ciriano-lab / SComatic

A tool for detecting somatic variants in single cell data
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How to remove the influence of different cell numbers #54

Open xinghua1001 opened 8 months ago

xinghua1001 commented 8 months ago

Hi,

Thank you for developing this smart tool. After using SComatic in my data, I found that there is a strong correlation between the mutation number and the cell number we used. So here is the question: when we compare mutations between groups with different cell numbers, how can we remove the effect of cell numbers. Is there any suggestion for this concern?

Best

XL