nsteinme
commented
7 years ago Hi Harish -
Your understanding of the probe specs are correct. There was a meeting at Janelia this summer to discuss making a version for non-human primate research, and it seems like an acute version - thick enough to enter the brain without resecting the dura - is likely to happen in the relatively near term. (Neuropixels have been demonstrated in NHP with dura removed, but it seems that this isn't a procedure one can undertake on a regular basis.) A longer acute version - 40mm was the number discussed at the meeting, too - is in planning stages but needs some testing of some of the technology required to make it. A chronic version - that could be implanted underneath the dura, floating on the brain like a Utah array, and would last indefinitely - is probably a major project that may or may not go forward. In any case, that is my summary of how the meeting went. I would encourage you and/or your P.I. to get in touch with Tim to stay up to date on the latest details regarding NHP probes.
On Thu, Nov 2, 2017 at 5:25 AM, harish2006 notifications@github.com wrote:
Hi, I am Harish, a post-doc in the Centre for Neuroscience at IISc Bangalore. Given the rather high yield of neuropixels probes, we were trying to understand whether it is suitable for chronic/acute recordings from structures such as IT cortex in the macaque brain. The probe specs on Github seem to indicate that the maximum probe length is 10 mm. Is there a version that allows for longer penetration, perhaps with some custom guide tubes ? We are looking at depths of 40 mm or so. The related papers seem to be on rodent models. Some constructive feedback on this will be great! Also, cheers for the Neuropixels team in general for coming up with this cost-effective and high throughput solution. Quite excited about this.
best, harish
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Hi, I am Harish, a post-doc in the Centre for Neuroscience at IISc Bangalore. Given the rather high yield of neuropixels probes, we were trying to understand whether it is suitable for chronic/acute recordings from structures such as IT cortex in the macaque brain. The probe specs on Github seem to indicate that the maximum probe length is 10 mm. Is there a version that allows for longer penetration, perhaps with some custom guide tubes ? We are looking at depths of 40 mm or so. The related papers seem to be on rodent models. Some constructive feedback on this will be great! Also, cheers for the Neuropixels team in general for coming up with this cost-effective and high throughput solution. Quite excited about this.
best, harish