search

cov-lineages / pango-designation

Repository for suggesting new lineages that should be added to the current scheme
Other
1.04k stars 98 forks source link

BA.4.6 sublineage with S:V445A, ORF1a:D1323G (29 seq., Dominican Republic, USA) #1198

Closed agamedilab closed 2 years ago

agamedilab commented 2 years ago

Proposal for a sublineage of BA.4.6 Earliest sequence: 11.08.2022 (Dominican Republic) Countries detected: USA (18), Dominican Republic (11)

T22896C = S:V445A A4233G = ORF1a:D1323G

This sublineage of BA.4.6 is defined by S:V445A, ORF1a:D1323G and was first detected in the Dominican Republic and the USA.

grafik https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice2_genome_c818_3be450.json?branchLabel=aa%20mutations&c=gt-S_445&label=nuc%20mutations:A4233G

grafik https://cov-spectrum.org/explore/World/AllSamples/Past3M/variants?aaMutations=S%3AV445A&nucMutations=A4233G&nextcladePangoLineage=BA.4.6*&aaMutations1=Orf3a%3AH78Y&pangoLineage1=BA.2*&

EPI_ISL_14614301 EPI_ISL_14805807 EPI_ISL_15105985 EPI_ISL_15146564 EPI_ISL_15146568 EPI_ISL_15164585 EPI_ISL_15164596 EPI_ISL_15164608 EPI_ISL_15164647 EPI_ISL_15205767 EPI_ISL_15205919 EPI_ISL_15205936 EPI_ISL_15206001 EPI_ISL_15226157 EPI_ISL_15256123 EPI_ISL_15256124 EPI_ISL_15256126 EPI_ISL_15296659 EPI_ISL_15296840 EPI_ISL_15296985 EPI_ISL_15297952 OP437357.1 OP504141.1 OP544795.1 OP552321.1 OP552514.1 OP569991.1 OP582730.1 OP589927.1

corneliusroemer commented 2 years ago

Thanks, good proposal because despite being probably not competitive with BQ.1.1 and co, it seems to have significant share in an undersampled region.

agamedilab commented 2 years ago

I would be very happy if a designate label could be added to the issue. many thanks! @corneliusroemer @InfrPopGen