FedeGueli commented 1 year ago

While checking trees from Philippines i met this double headed XBB.1+486P lineage with two distinct branches one in Gujarat with S:Q613H and the other in England. All sequences seems very recent so maybe worth keeping an eyes on it.

Defining mutations: XBB.1> Orf8:G8*>C18744T>S:F486P (T23018C) then S:Q613H for the indian branch and instead for the english branch Orf1a:V274L (G1085T),G12331A,ORF8:P93L (C28171T)

Tree:

https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice13_genome_29215_da7400.json?c=gt-ORF8_8&label=id:node_5865699

Gisaid query: -A1846G, -C2710T,C18744T,T23018C,G22317T,-C1613A,-A3139G,-T12730A,-G5720A,-T17124C,-A8001G,

Sequences: 26

Expand for EPI_ISLs

EPI_ISL_17026904, EPI_ISL_17073060, EPI_ISL_17184360, EPI_ISL_17231307, EPI_ISL_17231348, EPI_ISL_17232515, EPI_ISL_17232523, EPI_ISL_17232525, EPI_ISL_17236453, EPI_ISL_17237978, EPI_ISL_17242107, EPI_ISL_17245914, EPI_ISL_17267176, EPI_ISL_17274016, EPI_ISL_17284451, EPI_ISL_17287146, EPI_ISL_17318646, EPI_ISL_17318648, EPI_ISL_17326247, EPI_ISL_17326262, EPI_ISL_17359928, EPI_ISL_17428021, EPI_ISL_17428043, EPI_ISL_17428059, EPI_ISL_17428190, EPI_ISL_17428239

On Usher tough there are more : 42 sequences:

Expand for more samples

EDITED in Gujarat its share seems hanging around 1% through March, but please keep in mind there is XBB.1.16 there already.

Mydtlwn commented 1 year ago

1929

FedeGueli commented 1 year ago

49 sequences now on Usher: https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_c5f2_af0050.json?c=userOrOld&label=id:node_5881767 Interestingly the last samples from india got S:T478R Schermata 2023-04-28 alle 00 01 30

FedeGueli commented 1 year ago

Growing very little notwithstanding the S:Q613H mutation. closing it fr the moment

cov-lineages / pango-designation

New XBB.1 + Orf8:G8* sublineage with S:F486P spreading in India (Gujarat) and England 49 sequences #1909

1929