XBB.1.44 with S:Y453F (33 seqs, 11 countries)

[NkRMnZr]

Transferred from sars-cov-2-variants/lineage-proposals#273

Defining Mutations: XBB.1.44 > A22920T(S:Y453F) Query: A22920T,C23802T,C21306T Earliest seq: 2023-03-16 (EPI_ISL_17775392, Xinjiang, China) Latest seq: 2023-08-22 (EPI_ISL_18211197, Oregon, USA) Sampled Countries: USA (8, Arkansas/2, Oregon/2, California/1, Florida/1, Illinois/1, Texas/1), Guatemala (3), Russia (2, Bryansk, Kaluga), Brazil (1, Parana), China (1, Xinjiang), Chile (1), India (1, Karnataka), Panama (1), Spain (1), Uruguay (1)

Genomes:

`EPI_ISL_17466542, EPI_ISL_17721507, EPI_ISL_17775392, EPI_ISL_17818239, EPI_ISL_17852293, EPI_ISL_17852326, EPI_ISL_17952330, EPI_ISL_17954575, EPI_ISL_17954587, EPI_ISL_17965646, EPI_ISL_17977446, EPI_ISL_17982601, EPI_ISL_18031797, EPI_ISL_18041143, EPI_ISL_18059863, EPI_ISL_18104288, EPI_ISL_18120284, EPI_ISL_18132108, EPI_ISL_18210477, EPI_ISL_18211197`

UShER: https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_8b3d_7264a0.json?label=id:node_7033845

Trivia:

• It (actually the whole XBB.1.44) may emerge in areas with low seqs, judging by its sparse distribution around the world.
• Another S:Y453F(A22920T) to watch.

[FedeGueli]

It is in the only no-486P XBB lineage which keeps spreading along with GD.1 and FW.1.1

[NkRMnZr]

Tracking updates

09-08, 1 sequence from California EPI_ISL_18232818

09-15, 5 seqs from USA

`EPI_ISL_18246590, EPI_ISL_18252614, EPI_ISL_18256131, EPI_ISL_18256576, EPI_ISL_18260342` https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_26735_436e40.json?f_userOrOld=uploaded%20sample&label=id:node_7069278  spilit of branches may caused by certain seqs with dropouts ``` Guatemala/1223-LNS/2023|EPI_ISL_17954177|2023-06-08 Guatemala/1331-LNS/2023|EPI_ISL_17954603|2023-06-12 Guatemala/1332-LNS/2023|EPI_ISL_17954604|2023-06-12 Guatemala/1970-DLNS/2023|EPI_ISL_18099375|2023-07-19 ``` 

09-23, 6 seqs from New Zealand, and USA

https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_a21f_edbb80.json?f_userOrOld=uploaded%20sample&label=id:node_7089390  `EPI_ISL_18265881, EPI_ISL_18269560, EPI_ISL_18270267, EPI_ISL_18270380, EPI_ISL_18276551, EPI_ISL_18292296`

[NkRMnZr]

no seqs