HK.12 with ORF1b:K2085E(nsp15_K34E) and S:Q14R (46 seqs, 8 countries)

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Defining Mutations: HK.12 > A19720G(ORF1b:K2085E), A21603G(S:Q14R) Query: A18492G, A19720G, A22629C Earliest seq: 2023-08-07 (EPI_ISL_18105537, Hubei, China) Latest seq: 2023-11-07 (EPI_ISL_18544061, Kanagawa, Japan) Sampled Countries: Canada (23: ON/22; SK), China (7: SH/4; HB; FJ; TW), Australia (4: NSW/3; WA), Japan (1), Singapore (1)

Genomes:

`EPI_ISL_18105537, EPI_ISL_18208539, EPI_ISL_18300640, EPI_ISL_18324891, EPI_ISL_18376452, EPI_ISL_18376876, EPI_ISL_18427813, EPI_ISL_18448106, EPI_ISL_18448111-18448112, EPI_ISL_18448114, EPI_ISL_18448119, EPI_ISL_18448327, EPI_ISL_18448399-18448401, EPI_ISL_18448403-18448404, EPI_ISL_18448655-18448658, EPI_ISL_18454478, EPI_ISL_18455809, EPI_ISL_18471378, EPI_ISL_18471382-18471384, EPI_ISL_18471388, EPI_ISL_18471464-18471465, EPI_ISL_18475269, EPI_ISL_18481139, EPI_ISL_18495095, EPI_ISL_18513794, EPI_ISL_18544061`

UShER: https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_ff69_5855c0.json?f_userOrOld=uploaded%20sample&label=id:node_3529227

Trivia:

• Formerly Branch 1 of multitask sars-cov-2-variants/lineage-proposals#1048 , later proven to be misplaced sub-branch of HK.12
• Already shown some spike diversity, including S:G482R and a saltation branch with A845S, I909V, D1084Y
• Growth probably skewed by Canadian sample density.

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Tracking updates

12-06, 7 seqs from 7 countreies: Australia, China, Japan, South Korea, New Zealand, Singapore and Thailand EPI_ISL_18556568, EPI_ISL_18556682, EPI_ISL_18562170, EPI_ISL_18564510, EPI_ISL_18566658, EPI_ISL_18589883, EPI_ISL_18590124

[NkRMnZr]

slow