cov-lineages / pango-designation

Repository for suggesting new lineages that should be added to the current scheme
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Proposal for large US Delta sub-lineage with Orf1b:183V (~80k sequences) #242

Closed corneliusroemer closed 3 years ago

corneliusroemer commented 3 years ago

New lineage proposal by @CorneliusRoemer

Description Sub-lineage of: B.1.617.2 (21J) Earliest sequence: Unclear, due to faulty dates in some sequences Most recent sequence: Current Countries circulating: Especially in the US, where it makes up 20% of all sequences, in Utah it reached even 70%

nuc:29700G ORF1b:183V nuc:14014G nuc:6040T

image

https://cov-spectrum.ethz.ch/explore/United%20States/AllSamples/AllTimes/variants/json=%7B%22variant%22%3A%7B%22name%22%3A%22B.1.617.2*%22%2C%22mutations%22%3A[%22Orf1b%3A183V%22]%7D%2C%22matchPercentage%22%3A1%7D

Interesting geographical distribution in US: image

Genomes (~80k) ORF1b:183V-nuc:6040T.intersection.txt

Evidence image https://nextstrain.org/groups/neherlab/ncov/global?c=gt-ORF1b_183

Proposed lineage name AY.x

chrisruis commented 3 years ago

Thanks @corneliusroemer We've added this as AY.44 in v1.2.87 to start on the branch with C6040T and therefore coincide with the introduction(s) into the USA. AY.44 has 19548 sequence designations.