GK.1.1.1 with ORF1b:A647S (nsp12_A656S), S:F157L and S:N450D (57 seqs, 7 countries)

[NkRMnZr]

Transferred from sars-cov-2-variants/lineage-proposals#1199

Defining Mutations: GK.1.1.1 > G15406T(ORF1b:A647S) > T8761C, C22033A(S:F157L), A22910G(S:N450D) Query: T8761C, G15406T, C22033A Earliest seq: 2023-10-05 (EPI_ISL_18654757, Córdoba, Argentina) Latest seq: 2023-12-27 (EPI_ISL_18759787, Louisiana, USA) Sampled Countries: USA (37: LA/26; NY/3; TX/2; CA; CO; IL; MI; MN; NJ), Argentina (6), Switzerland (6), New Zealand (3) Austria (2), UK (2: EN, SC), Chile (1)

Genomes:

`EPI_ISL_18445782, EPI_ISL_18445785, EPI_ISL_18445787, EPI_ISL_18470206-18470207, EPI_ISL_18470209, EPI_ISL_18485433, EPI_ISL_18486058, EPI_ISL_18497614, EPI_ISL_18529004, EPI_ISL_18545716, EPI_ISL_18546316, EPI_ISL_18546320, EPI_ISL_18547051, EPI_ISL_18547089, EPI_ISL_18596891, EPI_ISL_18600764, EPI_ISL_18606112, EPI_ISL_18608858, EPI_ISL_18608861-18608865, EPI_ISL_18608867, EPI_ISL_18622126, EPI_ISL_18622519, EPI_ISL_18639114, EPI_ISL_18644941, EPI_ISL_18654755-18654757, EPI_ISL_18654781, EPI_ISL_18654789, EPI_ISL_18656996, EPI_ISL_18669940, EPI_ISL_18670350, EPI_ISL_18670504, EPI_ISL_18670963, EPI_ISL_18670978, EPI_ISL_18677357, EPI_ISL_18688465, EPI_ISL_18690257, EPI_ISL_18713498, EPI_ISL_18714247, EPI_ISL_18731326, EPI_ISL_18759774, EPI_ISL_18759777-18759781, EPI_ISL_18759783-18759785, EPI_ISL_18759787-18759788`

UShER: https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_f0a7_379bf0.json?label=id:node_3756797

Trivia:

• Most seqs from Louisiana, USA also has ins28250CT, T28251G (gisaid) or ins28250CTG (nextclade) that causes end of ORF8 frameshift

[FedeGueli]

60 now, none from january tough

[xz-keg]

66 now, and includes some Jan seqs.

[FedeGueli]

68 now

[FedeGueli]

74 now ping @corneliusroemer i think this deserves a designation.

[FedeGueli]

91 now with a quite big upload from Argentina. representing 5/158 samples collected there in January

[DailyCovidCases]

Please close this issue