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Repository for suggesting new lineages that should be added to the current scheme
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XBB.1.16.6/HV.1.2 Sandwich Recombinant (35 sequences, CA 30, US 5) #2472

Closed Over-There-Is closed 4 months ago

Over-There-Is commented 6 months ago

Transferred from sars-cov-2-variants/lineage-proposals#1137, first spotted by @corneliusroemer

XBB.1.16.6/HV.1.2/XBB.1.16.6

Query: A10861G, C18508T, C23103T

Earliest sequence: 10-18 Saskatchewan, Canada EPI_ISL_18501595 Latest sequence: 01-08 Saskatchewan, Canada EPI_ISL_18930012 Regions detected: Canada 30(Saskatchewan 24, Alberta 5, BC 1), US 5(Texas 4, California 1)

XBB.1.16.6+A10861G(The branch with JF.1/2) HV.1.2+C18508T(Orf1b:L1681F)(167 seq) Breakpoint 1: 12789\~14856 Breakpoint 2: 23103\~27507 Mutations based on XBB.1+Orf8:G8*+Orf9b:I5T+S:S486P: C8947T, A10861G, C11750T(Orf1a:L3829F), C11956T, A12397G, T12730A / A16878T, A18492G, C18508T(Orf1b:L1681F), G21718T(S:Q52H), C22033A(S:F157L), C22480T, T22917G(S:L452R), T22930A(S:F456L), C23103T(S:S514F) / A28447G(Orf9b:N55S), C29386T

17 sequences have private A1065G(Orf1a:N267S), and the other 7 have no coverage on 1065, so all sequences have A1065G potentially.

https://nextstrain.org/fetch/github.com/Over-There-Is/subtreeAuspice/raw/main/subtreeAuspice_genome_214c4_fdd5d0.json?label=id:node_3312674 2024-01-24 (1)

Sequences: EPI_ISL_18492983, EPI_ISL_18501595, EPI_ISL_18532465, EPI_ISL_18538454, EPI_ISL_18538782, EPI_ISL_18608945, EPI_ISL_18677936, EPI_ISL_18689986, EPI_ISL_18690001, EPI_ISL_18707203, EPI_ISL_18719564, EPI_ISL_18719656, EPI_ISL_18719678, EPI_ISL_18719761, EPI_ISL_18743301, EPI_ISL_18757767, EPI_ISL_18757774, EPI_ISL_18757777, EPI_ISL_18757810, EPI_ISL_18787525, EPI_ISL_18797438, EPI_ISL_18797457, EPI_ISL_18797488, EPI_ISL_18797550, EPI_ISL_18816881, EPI_ISL_18819010, EPI_ISL_18819014, EPI_ISL_18819031, EPI_ISL_18848626, EPI_ISL_18848658, EPI_ISL_18848664, EPI_ISL_18929958, EPI_ISL_18930012, EPI_ISL_18930058, EPI_ISL_18930111