JN.1.4.3 (S:T572I) with S:R346T (66-US)

[FedeGueli]

Transferred from Branch 8 of https://github.com/sars-cov-2-variants/lineage-proposals/issues/1097

Original proposal

Defining mutations: JN.1.4 > S:t572I (C23277T) Query: C774T,C23277T, -T18453C,-C3177T,-C4327T,-G25445A,-T5389C,-C2980T Samples: 28 Tree: https://nextstrain.org/fetch/genome-test.gi.ucsc.edu/trash/ct/subtreeAuspice2_genome_test_403e1_f87880.json?c=userOrOld&label=id:node_6928638

Important: This got a sub-lineage with S:R346T (even if it could be an independent one) :
Query: C774T,G22599C, C23277T,-C2980T,C18894T Samples 6 (US-4 states) EPI_ISL_18818630, EPI_ISL_18826826, EPI_ISL_18849701, EPI_ISL_18859307, EPI_ISL_18866094, EPI_ISL_18867924, Tree:

https://nextstrain.org/fetch/genome-test.gi.ucsc.edu/trash/ct/singleSubtreeAuspice_genome_test_59c9e_341240.json?label=id:node_6860926

[FedeGueli]

ping @corneliusroemer this got 346T too, growing, 6 seqs from 4 different states in Us

[Fearuncle]

jn.1.4 + S:T572I + s:346T is now 9

[Fearuncle]

[FedeGueli]

jn.1.4 + S:T572I + s:346T is now 9

thank you

[corneliusroemer]

JN.1.4.3, I haven't designated the 346T yet, just the 572I

Let's wait a bit more with 346T until it's something like 25

[FedeGueli]

+5 Us (4 Ga, 1 FLA)

[FedeGueli]

20 now +5 Georgia California Texas. ping @corneliusroemer it seems expanding both for number of samples and number of States . maybe worth designating it.

[xz-keg]

30 now

[FedeGueli]

30 now

Thank you @aviczhl2 , @corneliusroemer this seems fast taking it with many caveats being concentrated in high sequencing areas: https://cov-spectrum.org/explore/World/AllSamples/Past3M/variants?%2FAllSamples%2FPast3M%2Fvariants%3FnextcladePangoLineage=JN.1*&nextcladePangoLineage=JN.1*&nucMutations1=C774T%2CG22599C%2CC2327

7T%2CC18894T%2CC2980C&analysisMode=CompareToBaseline&

[FedeGueli]

36

[FedeGueli]

59 very fast.

[FedeGueli]

66 fast still US mainly but different states especially GA

[FedeGueli]

Designated KQ.1 via https://github.com/cov-lineages/pango-designation/commit/a528c797030e5fa63be113b1726ab0947dba92c1