cov-lineages / pango-designation

Repository for suggesting new lineages that should be added to the current scheme
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JN.1.18+S:F456V misplaced as JN.1.16.1+S:L456V(109 seqs, 19 countries) #2538

Closed aviczhl2 closed 1 month ago

aviczhl2 commented 3 months ago

From branch 37 of https://github.com/sars-cov-2-variants/lineage-proposals/issues/1253 and https://github.com/sars-cov-2-variants/lineage-proposals/issues/1437

JN.1.18+S:F456V(T22928G)

GISAID query: G22599C, T22928G,C18894T, -6705,-C774T,-25658,-7789 No. of seqs: 5(USA 3 Singapore 1(from Saudi Arabia) Bangladesh 1)

First: EPI_ISL_18851598, Singapore from Saudi Arabia, 2024-1-12 Latest: EPI_ISL_19011021, USA, 2024-3-16

Usher places it in JN.1.16.1(R346T+F456L)+S:L456V (C22928G) . However that means position 22928 has to mutate from T->C->G in a short time, which is highly unlikely. @AngieHinrichs @corneliusroemer

A better explanation shall be JN.1.18(R346T)+S:F456V(T22928G).

usher

image

FedeGueli commented 3 months ago

Thank you i noticed you havve excluded a couple more of convergent lineages are they among the ones already tracked?

aviczhl2 commented 3 months ago

Thank you i noticed you havve excluded a couple more of convergent lineages are they among the ones already tracked?

No. They are singlets, one under JN.1.30.1 and another under an undesignated JN,1 branch

FedeGueli commented 3 months ago

Thank you i noticed you havve excluded a couple more of convergent lineages are they among the ones already tracked?

No. They are singlets, one under JN.1.30.1 and another under an undesignated JN,1 branch

thx just checked one is Singlet 6 of # 1089 while the other is unknown till you spotted i will add with credits to the tracking issue

FedeGueli commented 3 months ago

7 now two more GBW one from NZL

aviczhl2 commented 3 months ago

+1 Canada

aviczhl2 commented 2 months ago

14, India

aviczhl2 commented 2 months ago

20, Australia

FedeGueli commented 2 months ago

21

FedeGueli commented 2 months ago

24 now (+4 with 2 from Qatar ) ping @corneliusroemer

FedeGueli commented 2 months ago

31 now @corneliusroemer i suggest to designate this one.

FedeGueli commented 2 months ago

35 now with 4 new sequences coming from New Zealand, i suggest designating it.

FedeGueli commented 2 months ago

36 now last from England

aviczhl2 commented 2 months ago

37, Japan, UK,

FedeGueli commented 2 months ago

the fastest FViRT: https://cov-spectrum.org/explore/World/AllSamples/Past3M/variants?%2FAllSamples%2FPast3M%2Fvariants%3FnextcladePangoLineage=JN.1*&nextcladePangoLineage=JN.1*&nucMutations1=G22599C%2CT22928G%2CC18894T%2CC774C%2C6705A%2C25658C%2C7789T&analysisMode=CompareToBaseline&

FedeGueli commented 2 months ago

43 (+6 California,Illinois, NJ, Queensland, England )

FedeGueli commented 2 months ago

53 +6 South Australia +3 Canada +1 Sweden

FedeGueli commented 2 months ago

59 (5 England +1 Japan)

FedeGueli commented 2 months ago

One of the UK sequences got S:S31Del and two additional spike mutations Jn.1.18>S:f456V > C13620T > 11749G, T21610C, S:R190S (G22132T),S:E780A (A23901C), C27649T, ORF10:N36S(A29664G) Query: del21653, C13620T

aviczhl2 commented 2 months ago

65, South Korea, UAE,

FedeGueli commented 1 month ago

83

FedeGueli commented 1 month ago

88, designation needed

FedeGueli commented 1 month ago

106 in 17 countries + airports samples that i didnt count in countries ,now ping @corneliusroemer now also Australia and New Zealand

aviczhl2 commented 1 month ago

109, Thailand, Peru, Germany, Norway, Brazil

FedeGueli commented 1 month ago

+1 Jap

aviczhl2 commented 1 month ago

Designated JN.1.18.3

FedeGueli commented 1 month ago

Jn.1.18.3 via https://github.com/cov-lineages/pango-designation/commit/978a25ac55834715bbb2c9e1fa209aa70e64631b