cozygene / FEAST

Fast expectation maximization for microbial source tracking
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How to calculate the count value of metaOTU? #38

Open timeresistance1996 opened 2 years ago

timeresistance1996 commented 2 years ago

It can be seen from the author's article (https://www.nature.com/articles/s41592-019-0431-x) that the first data uses metagenomic-recovered mataOTUs for the feast analysis. Relative abundances are calculated as decimals and unable to proceed to the next feast analysis. I don't know how to calculate the integer count value of mataOTU. I'm confused, any answer is greatly appreciated!

liashenhav commented 2 years ago

We followed the methods section of the original paper generated the data: Backhed, F. et al. Dynamics and stabilization of the human gut microbiome during the first year of life. Cell Host Microbe 17, 690–703 (2015)