`addSpacerAlignmentsIterative` – Error in `curl::curl_fetch_memory`

[abearab]

When I run alignment a few times (trying to troubleshot my codes), I get this error:

R[write to console]: Error in curl::curl_fetch_memory(url, handle = handle) : 
  Timeout was reached: [[www.ensembl.org:443](https://www.ensembl.org/)] Operation timed out after 10002 milliseconds with 514839 bytes received

[Jfortin1]

Hi @abearab, could you share your reproducible code with me?

[abearab]

Hello, this is my code:

%%R 
guideSet <- addSpacerAlignmentsIterative(
    guideSet,
    txObject=txdb,
    aligner_index=bowtie_index,
    bsgenome=bsgenome,
    n_mismatches=2
)

Although, I changed my wifi network and tried again.. I could make it work.

[Jfortin1]

ah yes, downloads from Ensembl don't always work depending on the internal connection. Closing this.